Vitamin B12 plays a key role in the normal functioning of nerve cells and blood cells. It is also involved in the metabolism of all types of body cells, it's mainly affecting DNA regulation and synthesis. Vitamin B12, also called cobalamin, contains molecules of the metal cobalt and corrin ring.
Absorption
The process of absorption of vitamin B12 is complex one, and because of that, it often leads to vitamin B12 deficiency. Vitamin B12 absorption begins in the mouth through the mucosa membrane. Acid in the stomach releases the vitamin B12 that is bound to the protein in food during digestion.
Recommended Dosage
The recommended dose for an adult ranges from 2 to 3 micrograms a day. Pregnant woman may require 3 micrograms per day.
Using B12 supplements is safe as long as the recommended dose is not exceeded.
The main source of vitamin B12 is animal foods including meat, fish, poultry, eggs and milk products, because of this, the Vegan Society recommends vegans to consistently eat B12 fortified foods or take a daily B12 supplements.
Food Sources
The main source of B12 comes from animal derived food, including meat, fish, poultry, eggs and milk products.
- 1 half chicken breast provides some 0.3µg per serving or 6.0% of the recommended daily value
- 3 ounces of beef provides 2.4 µg per serving or 40% of your DV
- 1 slice of liver provide 47.9 µg or 780% of your DV
- 3 ounces of Molluscs provides 84.1 µg, or 1,400 % of your DV
Side effects
Itching, rash, temporary exanthema, and urticaria have been reported. Vitamin B12 and pyridoxine has been associated with cases of rosacea fulminans, characterized by intense erythema with nodules, papules, and pustules. Symptoms may persist for up to four months after the supplement is stopped, it may require treatment with systemic corticosteroids and topical therapy.
Diarrhea has been reported.
Vitamin B12 as Pernicious Anemia treatment
Vitamin B12 is used for the treatment of pernicious anemia (AKA Biermer's anemia) which is caused by the deficiency of vitamin B12 . For the body to properly absorb the vitamin B12 it first has to be combined with the intrinsic factor (a glycoprotein produced in the stomach). The absence of intrinsic factor prevents the normal absorption of the vitamin B12 and usually result in pernicious anemia. The treatment for Pernicious anemia is for life; supplemental vitamin B12 can be administered via injection or orally.
David C. is the author of the Vitamin Supplement Blog, read more about vitamins and supplements at http://www.myvitaminsupplement.net
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